The past two Southern Athletic Association champions will battle Saturday afternoon at Young-Wise Memorial Stadium.
The Hendrix College Warriors (3-0, 1-0 SAA) won the title last season, while the Centre College Colonels (4-0, 2-0 SAA) took the crown in 2014.
Last year, he two teams played in a 51-48 shootout in Danville, Ky., which Hendrix won.
"It was a shootout through the first three quarters, but we controlled the clock in the fourth quarter and our defense stepped up," Hendrix coach Buck Buchanan said.
In that game, Hendrix running back Dayton Winn broke several school records, rushing for 283 yards and five touchdowns on 52 carries.
"Dayton had a great game," Buchanan said. "He was 90 percent of our offense in that game. Some of our other guys were banged up, but I think our guys are ready to go for this game."
The game is shaping up to be another fan-friendly game as the two teams boast the SAA’s top two offenses and defenses.
The Warriors are the conference’s top offense, posting 583 yards per game and scoring 48.7 points per game. Centre falls just behind Hendrix, averaging 563.5 ypg and scoring 44.8 ppg.
"There are two very good football teams going at it," Buck said. They are the consistent team in the conference and have a great program that’s backed by great coaching. If anyone is looking for a football game on Saturday, this is a good one to go to."
On the defensive side, the Colonels have given up fewer yards per game than the Warriors, averaging 355.3, while Hendrix is giving up 360.
However, the Warriors are giving up 17 ppg, which leads the conference, while Centre is second at 20.5 ppg.
The Colonels are backed on offense by quarterback Devin Hayes and running back Nolan Coulter.
The two players rank in the top three in their respective offensive statistical categories.
Hendrix counters by having quarterback Seth Peters and Winn.
Peters is playing his best season statistically to this point, completing almost 84 percent of his passes through three games.
Last week in the conference opener against Millsaps, he threw for 350 yards and four touchdowns to four different receivers. He finished the game completing 25 of 32 passes.