Hendrix sophomore guard Vinessa Daniel produced her third double-double of the season but it was not enough as Hendrix recorded just three points in the opening frame en route to the 60-46 defeat to Millsaps.
The Majors improve to 13-2 (4-0 Southern Athletic Association) while Hendrix falls to 9-6, 2-2 SAA).
After the Majors created a nine-point run in the first quarter the Warriors were unable to catch back up.
However, the Warriors did try to regain momentum at the end of the third quarter leading into the fourth by going on a ten-point run against Millsaps.
Hendrix shot just 4 of 38 and 1 for 17 from deep, but trailed by just 19.
Freshman guard Serena Pruitt and Daniel combined to score the first four points of the second half, but the Warriors trailed by 25 after three periods of play.
A 10-0 run in the opening 4:21 of the fourth quarter brought Hendrix within 15 points at 49-34.
After a Millsaps free throw, Hendrix went on a quick 6-0 run to trail by just 11 with 4:54 left.
Millsaps hit its final four free throws to get away with the 60-46 victory but Hendrix doubled up the Majors in the fourth, pouring in 22 fourth period points while Millsaps had just 11.
Daniel finished with a game-high 19 points and 10 boards en route to the third double-double of her career and also logged three steals and an assist.
Freshman forward Jayla King recorded a team-best 10 boards while scoring three points as well.
Sophomore forward Kessie Jenkins accounted for five points and five rebounds in 22 minutes of work while senior forward Maddie Anderson tallied five rebounds as well.
Hendrix shot 16 of 72 from the floor and 3 for 31 from deep while producing a 11 for 18 mark at the free-throw line while Millsaps recorded a 19 of 54 mark from the floor, 6 of 18 from downtown and 16 for 19 at the charity stripe.
Hendrix remains inside the confines of Grove Gymnasium as Birmingham-Southern comes to town Sunday afternoon.
The Warriors and the Panthers are set for a 1 p.m. tip. Coach Craig Kirchgessner and Coach Kristian Lenser will have the broadcast call.